You may be able to take part if you:

• are 18 years of age or older
• have very high blood fat levels (triglycerides ≥500 mg/dL or ≥5.65 mmol/L)
• agree to follow diet counseling and maintain a stable low-fat diet during the study.

People may experience SHTG in different ways based on their race, ethnicity, gender, age, and background. Having a diverse group of people in the clinical study will help us see how this investigational study drug works for different people.

You must meet all other study criteria to take part in the SHASTA Study.

If you do not meet the criteria for the SHASTA Study, you may be able to take part in a similar study called the MUIR Study. The MUIR Study is for people 18 years of age and older who have high blood fat levels (triglycerides of 150 to 499 mg/dL or 1.69 mmol/L to 5.64 mmol/L). You must meet all other study criteria to take part in the MUIR Study.